課程資訊
課程名稱
環境毒理學概論
Principles of Environmental Toxicology 
開課學期
100-1 
授課對象
公共衛生學院  環境衛生研究所  
授課教師
林靖愉 
課號
EH5019 
課程識別碼
844EU1280 
班次
 
學分
全/半年
半年 
必/選修
選修 
上課時間
星期四5,6(12:20~14:10) 
上課地點
公衛210 
備註
本課程以英語授課。與吳焜裕合開
總人數上限:30人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1001EnvTox 
課程簡介影片
 
核心能力關聯
核心能力與課程規劃關聯圖
課程大綱
為確保您我的權利,請尊重智慧財產權及不得非法影印
課程概述

The course first introduces basic principles of toxicology. Physicochemical properties of toxicants following fate processes (absorption, distribution, metabolism, and elimination), toxicokinetics, and toxicodynamics will be introduced. Factors affecting fate and response and mechanisms of toxic action will also be discussed. The course will then introduce fate of chemicals in the environment. Finally, modern techniques in toxicant metabolism and environmental toxicology will be discussed. 

課程目標
This is a selective course for students who are interested in environmental toxicology. Principles of toxicology will be first introduced. Fate processes of toxicants in the body, toxicokinetics, toxicodynamics, and mechanism of toxic action will be presented. Fate of chemicals in environment will also be discussed. Students will learn the basic concepts of toxicology and study the whole picture of fate processes of chemicals in both the body and environment. The prerequisite of this course is Organic Chemistry. 
課程要求
Midterm I 30%
Midterm II 30%
Final report 30%
Homework 10% 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
 
參考書目
 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
Week 1
09/15  Introduction; Principles of toxicology 
Week 2
09/22  Physicochemical properties of toxicants 
Week 3
09/29   Fate processes in the body –absorption, distribution 
Week 4
10/06  Fate processes in the body –metabolism 
Week 5
10/13  Fate processes in the body –elimination 
Week 6
10/20  Midterm exam 1 
Week 7
10/27  Factors affecting fate and response 
Week 8
11/03   Toxicokinetics, PBPK 
Week 9
11/10   Toxicodynamics (attending workshop) 
Week 10
11/17  Mechanisms of toxic action (I) 
Week 11
11/24   Mechanisms of toxic action (II) 
Week 12
12/01  Midterm exam 2 
Week 13
12/08  Fate processes in environment - chemical principles & biological applications  
Week 14
12/15  Modern techniques in studying toxicology (Lab tour) 
Week 15
12/22  Risk assessment (I) (Wu) 
Week 16
12/29  Risk assessment (II) (Wu) 
Week 17
01/05  Current toxicological issues in Taiwan (Wu) 
Week 18
01/12  Final exam